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Article

Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts.

The Journal of allergy and clinical immunology - 1 Nov 2015

Park Heung-Woo, Ge Bing, Tse Szeman, Grundberg Elin, Pastinen Tomi, Kelly H William, Tantisira Kelan G

Abstract excerpt

BACKGROUND: Long-term intermittent oral corticosteroid (OCS) use in children with asthma leads to significant decreases in bone mineral accretion (BMA). OBJECTIVE: We aimed to identify genetic factors influencing OCS dose effects on BMA in children with asthma. METHODS: We first performed a gene-by-OCS interaction genome-wide association study (GWAS) of BMA in 489 white participants in the Childhood Asthma...

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Source

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Identifiers

PMID: 26025128
DOI: 10.1016/j.jaci.2015.04.014
PMCID: PMC4641004

Genes

TBCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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