Article
ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jun 2015
Vijverberg S J H, Koster E S, Tavendale R, Leusink M, Koenderman L, Raaijmakers J A M, Postma D S, Koppelman G H, Turner S W, Mukhopadhyay S, Tse S M, Tantisira K G, Hawcutt D B, Francis B, Pirmohamed M, Pino-Yanes M, Eng C, Burchard E G, Palmer C N A, Maitland-van der Zee A H
Abstract excerpt
BACKGROUND: The clinical response to inhaled corticosteroids (ICS) is associated with single nucleotide polymorphisms (SNPs) in various genes. This study aimed to relate variations in genes in the steroid pathway and asthma susceptibility genes to exacerbations in children and young adults treated with ICS. METHODS: We performed a meta-analysis of three cohort studies: Pharmacogenetics of Asthma Medication in...
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