Article
The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids.
The Journal of allergy and clinical immunology - 1 Jun 2009
Hawkins Gregory A, Lazarus Ross, Smith Richard S, Tantisira Kelan G, Meyers Deborah A, Peters Stephen P, Weiss Scott T, Bleecker Eugene R
Abstract excerpt
BACKGROUND: Corticosteroids exert their anti-inflammatory action by binding and activating the intracellular glucocorticoid receptor heterocomplex. OBJECTIVE: We sought to evaluate the genes HSPCB, HSPCA, STIP1, HSPA8, DNAJB1, PTGES3, FKBP5, and FKBP4 on corticosteroid response. METHODS: White as...
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