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Article

Novel genetic variants associated with inhaled corticosteroid treatment response in older adults with asthma

2 May 2022

Abstract excerpt

Introduction Older adults have the greatest burden of asthma and poorest outcomes. The pharmacogenetics of inhaled corticosteroid (ICS) treatment response is not well studied in older adults. Methods A genome-wide association study of ICS response was performed in asthmatics of European ancestry in Genetic Epidemiology Research on Adult Health and Aging (GERA) by fitting Cox proportional hazards regression...

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PMID: 35501119
DOI: 10.1136/thoraxjnl-2021-217674

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