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Article

Differential reactivation of fetal/neonatal genes in mouse liver tumors induced in cirrhotic and non‐cirrhotic conditions

25 May 2015

Abstract excerpt

Hepatocellular carcinoma develops in either chronically injured or seemingly intact livers. To explore the tumorigenic mechanisms underlying these different conditions, we compared the mRNA expression profiles of mouse hepatocellular tumors induced by the repeated injection of CCl4 or a single diethylnitrosamine (DEN) injection using a cDNA microarray. We identified tumor-associated genes that were expressed...

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PMID: 26011625
DOI: 10.1111/cas.12700

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