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Article

Genetic and epigenetic changes in fibrosis‐associated hepatocarcinogenesis in mice

15 Nov 2013

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of the most prevalent cancers and is rising in incidence worldwide. The molecular mechanisms leading to the development of HCC are complex and include both genetic and epigenetic events. To determine the relative contribution of these alterations in liver tumorigenesis, we evaluated epigenetic modifications at both global and gene specific levels, as well as the mutational...

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PMID: 24242335
DOI: 10.1002/ijc.28610

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