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Integrative genomic analysis of mouse and human hepatocellular carcinoma

3 Oct 2018

Abstract excerpt

Cancer genomics has enabled the exhaustive molecular characterization of tumors and exposed hepatocellular carcinoma (HCC) as among the most complex cancers. This complexity is paralleled by dozens of mouse models that generate histologically similar tumors but have not been systematically validated at the molecular level. Accurate models of the molecular pathogenesis of HCC are essential for biomedical progress;...

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PMID: 30287485
DOI: 10.1073/pnas.1811029115

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