Article
Serotonin gene polymorphisms and lifetime mood disorders in predicting interferon-induced depression in chronic hepatitis C.
Journal of affective disorders - 1 Sept 2015
Cozzolongo Raffaele, Porcelli Piero, Cariola Filomena, Giannuzzi Vito, Lanzilotta Elsa, Gentile Mattia, Sonnante Gabriella, Leandro Gioacchino
Abstract excerpt
BACKGROUND: IFN-induced depression is a suitable model for investigating vulnerability to depression. We aimed at investigating the role of two vulnerability factors, lifetime mood disorder (LMD) and 5-HT-related gene polymorphisms in treated patients with infection by Hepatitis C Virus (HCV). METHODS: Depressive symptoms of 130 consecutive HCV patients with no current psychopathology were measured during...
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