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Article

Risk for depression during interferon-alpha treatment is affected by the serotonin transporter polymorphism.

Biological psychiatry - 15 Feb 2009

Lotrich Francis E, Ferrell Robert E, Rabinovitz Mordechai, Pollock Bruce G

Abstract excerpt

BACKGROUND: Major depressive disorder (MDD) occurs in a subset of patients receiving interferon-alpha treatment, although many are resilient to this side effect. Genetic differences in the serotonin reuptake transporter promoter (5-HTTLPR) may interact with the inflammatory system and influence d...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18801474
DOI: 10.1016/j.biopsych.2008.08.009
PMCID: PMC2654233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18801474-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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