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Article

A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-alpha treatment.

Psychosomatics - 1 Jan 2000

Pierucci-Lagha Amira, Covault Jonathan, Bonkovsky Herbert L, Feinn Richard, Abreu Christine, Sterling Richard K, Fontana Robert J, Kranzler Henry R

Abstract excerpt

BACKGROUND: Interferon-alpha (IFN-alpha) treatment frequently induces depression, potentially leading to early dose reductions or a shorter duration of treatment, which can adversely affect outcomes, including quality of life. OBJECTIVE: Defining relevant risk factors for IFN-alpha-induced depres...

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Identifiers

PMID: 20332289
DOI: 10.1176/appi.psy.51.2.137
PMCID: PMC3746312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20332289-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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