Article
Serotonin-1A receptor CC genotype is associated with persistent depression related to interferon-alpha in hepatitis C patients.
General hospital psychiatry - 1 Jan 2000
Galvão-de Almeida Amanda, Quarantini Lucas C, Tartaglioni Amanda Guindalini, Lyra André C, Parise Carmen Lívia, Paraná Raymundo, de Oliveira Irismar R, Miranda-Scippa Angela, Guindalini Camila
Abstract excerpt
OBJECTIVE: The aim of this study is to investigate the development of depression during interferon-alpha (IFN-α) therapy and the variations in the expression of the serotonin receptor (5-HTR) and transporter (5-HTT) in hepatitis C patients. METHOD: Hepatitis C patients (n=277) were given the Mini International Neuropsychiatric Interview at the end of IFN-α therapy. Three polymorphisms were genotyped: the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
