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Article

Serotonin and interleukin-6: the role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms.

Psychoneuroendocrinology - 1 Sept 2013

Udina Marc, Moreno-España José, Navinés Ricard, Giménez Dolors, Langohr Klaus, Gratacòs Mònica, Capuron Lucile, de la Torre Rafael, Solà Ricard, Martín-Santos Rocío

Abstract excerpt

BACKGROUND: Cytokines and serotonin neurotransmission may play an important role on the development of psychopathological symptoms during interferon (IFN) treatment. The aim of the present study was to investigate the association between IFN-induced depression, anxiety and fatigue and functional genetic variants at the interleukin-6 gene (IL-6) and serotonin transporter gene (SERT). METHODS: 385 consecutive...

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PMID: 23571152
DOI: 10.1016/j.psyneuen.2013.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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