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Article

Serotonin-1A receptor gene HTR1A variation predicts interferon-induced depression in chronic hepatitis C.

Gastroenterology - 1 Apr 2007

Kraus Michael R, Al-Taie Oliver, Schäfer Arne, Pfersdorff Matthias, Lesch Klaus-Peter, Scheurlen Michael

Abstract excerpt

BACKGROUND & AIMS: Interferon-induced depression is a major complication in antiviral therapy of chronic hepatitis C. Little is known about underlying mechanisms and reliable predictive factors associated with cytokine-induced depressive symptoms. METHODS: In a cohort of 139 hepatitis C-infected outpatients treated with interferon alfa-2b, we investigated the impact of functional gene variants of the cerebral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17408646
DOI: 10.1053/j.gastro.2007.02.053

Genes

HTT
TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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