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Article

Interferon-gamma (+874) T/A genotypes and risk of IFN-alpha-induced depression.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Feb 2011

Oxenkrug G, Perianayagam M, Mikolich D, Requintina P, Shick L, Ruthazer R, Zucker D, Summergrad P

Abstract excerpt

Depression is a frequent side effect of interferon (IFN)-alpha therapy of hepatitis C (HCV) and is of great relevance with regard to adherence, compliance, and premature therapy discontinuation. There are no reliable tests to identify patients-at-risk for the development of IFN-alpha induced depression. We retrospectively studied distribution of IFN-gamma (IFNG) (+874) T/A genotypes in 170 Caucasian HCV patients...

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Source

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Identifiers

PMID: 21161299
DOI: 10.1007/s00702-010-0525-1
PMCID: PMC3079262

Genes

IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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