Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sustained virological response in the antiviral therapy of chronic hepatitis C: is there a predictive value of interferon-induced depression?

Chemotherapy - 1 Jan 2007

Schäfer Arne, Scheurlen Michael, Weissbrich Benedikt, Schöttker Katrin, Kraus Michael R

Abstract excerpt

BACKGROUND: The study objective was to determine the contribution of cytokine-induced depression to a predictive model of sustained virological response (SVR) in chronic hepatitis C. METHODS: One hundred and one therapy-naïve hepatitis C virus (HCV) outpatients received treatment with peginterferon alfa-2b and ribavirin. Neuropsychiatric side effects were monitored prospectively (Hospital Anxiety and Depression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Depression
Share to Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Interferon-alpha

Share to Interferon alpha-2

Share to Logistic Models

Share to Polyethylene Glycols

Share to Ribavirin

Source

Identifiers

PMID: 17496415
DOI: 10.1159/000102584

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sustained virological response in the antiviral therapy of chronic hepatitis C: is there a predictive value of interferon-induced depression?PMID 17496415Read ↗

The Severity of Depressive Symptoms as an Independent Predictor of Sustained Virological Response During Treatment of Hepatitis C With Pegylated Interferon-α2a and Oral Ribavirin.Semantic proximity Read ↗

Impact of depressive symptoms and their treatment on completing antiviral treatment in patients with chronic hepatitis C.Semantic proximity Read ↗

Biological mechanisms of depression following treatment with interferon for chronic hepatitis C: A critical systematic review.Semantic proximity Read ↗

Selective Hyper-responsiveness of the Interferon System in Major Depressive Disorders and Depression Induced by Interferon TherapySemantic proximity Read ↗

Lack of association of indoleamine 2,3-dioxygenase polymorphisms with interferon-alpha-related depression in hepatitis C.Semantic proximity Read ↗

Serotonin gene polymorphisms and lifetime mood disorders in predicting interferon-induced depression in chronic hepatitis C.Semantic proximity Read ↗

Genotype 1 of hepatitis C virus increases the risk of major depression: a 12-week prospective study.Semantic proximity Read ↗

Glucocorticoid Receptors, Brain-Derived Neurotrophic Factor, Serotonin and Dopamine Neurotransmission are Associated with Interferon-Induced Depression.Semantic proximity Read ↗

Transcriptomics in Interferon-α-Treated Patients Identifies Inflammation-, Neuroplasticity- and Oxidative Stress-Related Signatures as Predictors and Correlates of DepressionSemantic proximity Read ↗

Serotonin-1A receptor gene HTR1A variation predicts interferon-induced depression in chronic hepatitis C.Semantic proximity Read ↗

Hepatitis C treatment in "difficult-to-treat" psychiatric patients with pegylated interferon-alpha and ribavirin: response and psychiatric side effects.Semantic proximity Read ↗

A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-alpha treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.