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Article

Biological mechanisms of depression following treatment with interferon for chronic hepatitis C: A critical systematic review.

Journal of affective disorders - 1 Feb 2017

Machado Myrela O, Oriolo Giovanni, Bortolato Beatrice, Köhler Cristiano A, Maes Michael, Solmi Marco, Grande Iria, Martín-Santos Rocío, Vieta Eduard, Carvalho André F

Abstract excerpt

BACKGROUND: A significant subset of patients infected by the hepatitis C virus (HCV) develops a major depressive episode (MDE) during Interferon-alpha (IFN-α) based immunotherapy. We performed a systematic review of studies which examined biological mechanisms contributing to the onset of a MDE during IFN-α-based immunotherapy for HCV. METHODS: Major electronic databases were searched from inception up until 15th...

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Source

Identifiers

PMID: 27936453
DOI: 10.1016/j.jad.2016.11.039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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