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Article

Age-Based Differences in the Genetic Determinants of Glycemic Control: A Case of FOXO3 Variations.

PloS one - 1 Jan 2015

Sun Liang, Hu Caiyou, Qian Yu, Zheng Chenguang, Liang Qinghua, Lv Zeping, Huang Zezhi, Qi Keyan, Huang Jin, Zhou Qin, Yang Ze

Abstract excerpt

BACKGROUND: Glucose homeostasis is a trait of healthy ageing and is crucial to the elderly, but less consideration has been given to the age composition in most studies involving genetics and hyperglycemia. METHODS: Seven variants in FOXO3 were genotyped in three cohorts (n = 2037; LLI, MI_S and MI_N; mean age: 92.5 ± 3.6, 45.9 ± 8.2 and 46.8 ± 10.3, respectively) to compare the contribution of FOXO3 to fasting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25993007
DOI: 10.1371/journal.pone.0126696
PMCID: PMC4439071

Genes

FOXO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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