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Article

Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity.

Mechanisms of ageing and development - 1 Oct 2018

Revelas Mary, Thalamuthu Anbupalam, Oldmeadow Christopher, Evans Tiffany-Jane, Armstrong Nicola J, Kwok John B, Brodaty Henry, Schofield Peter R, Scott Rodney J, Sachdev Perminder S, Attia John R, Mather Karen A

Abstract excerpt

BACKGROUND: Many factors contribute to exceptional longevity, with genetics playing a significant role. However, to date, genetic studies examining exceptional longevity have been inconclusive. This comprehensive review seeks to determine the genetic variants associated with exceptional longevity by undertaking meta-analyses. METHODS: Meta-analyses of genetic polymorphisms previously associated with exceptional...

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Identifiers

PMID: 29890178
DOI: 10.1016/j.mad.2018.06.002

Genes

APOE
ACE

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