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Article

Genetic Association Analysis of Common Variants in FOXO3 Related to Longevity in a Chinese Population.

PloS one - 1 Jan 2016

Lin Rong, Zhang Yunxia, Yan Dongjing, Liao Xiaoping, Wang Xianshou, Fu Yunxin, Cai Wangwei

Abstract excerpt

Recent studies suggested that forkhead box class O3 (FOXO3) functions as a key regulator for the insulin/insulin-like growth factor-1signaling pathway that influence aging and longevity. This study aimed to comprehensively elucidate the association of common genetic variants in FOXO3 with human longevity in a Chinese population. Eighteen single-nucleotide polymorphisms (SNPs) in FOXO3 were successfully genotyped...

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Source

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Identifiers

PMID: 27936216
DOI: 10.1371/journal.pone.0167918
PMCID: PMC5148017

Genes

FOXO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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