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Article

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population.

Oncotarget - 5 Jan 2016

Li Ning, Luo Huaichao, Liu Xiaoqi, Ma Shi, Lin He, Chen Rong, Hao Fang, Zhang Dingding

Abstract excerpt

FOXO3, AKT1 and IGF-2R are critical members of the insulin/IGF-1 signaling pathway. Previous studies showed that polymorphisms (SNPs) in FOXO3, AKT1 and IGF-2R were associated with human longevity in Caucasian population. However, the association of these SNPs in different ethnic groups is often inconsistent. Here, we investigated the association of genetic variants in three genes with human longevity in Han...

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Source

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Identifiers

PMID: 26683100
DOI: 10.18632/oncotarget.6627
PMCID: PMC4807980

Genes

FOXO3
AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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