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Article

Association of the <i>FOXO3A</i> Locus with Extreme Longevity in a Southern Italian Centenarian Study

1 Apr 2009

Abstract excerpt

A number of potential candidate genes in a variety of biological pathways have been associated with longevity in model organisms. Many of these genes have human homologs and thus have the potential to provide insights into human longevity. Recently, several studies suggested that FOXO3A functions as a key bridge for various signaling pathways that influence aging and longevity. Interestingly, Willcox and...

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PMID: 19415983
DOI: 10.1089/rej.2008.0827

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