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Article

Genotype‑phenotype analysis of CYP2C19 in the Tibetan population and its potential clinical implications in drug therapy.

Molecular medicine reports - 1 Mar 2016

Jin Tianbo, Zhang Xiyang, Geng Tingting, Shi Xugang, Wang Li, Yuan Dongya, Kang Longli

Abstract excerpt

Cytochrome P450 2C19 (CYP2C19) is a highly polymorphic gene, it codes for a protein responsible for the metabolism of multiple clinically important therapeutic agents. However, there is currently no available data on the distribution of CYP2C19 mutant alleles in the Tibetan population. The aim of the present study was to identify different CYP2C19 mutant alleles and determine their frequencies, along with...

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Identifiers

PMID: 26781306
DOI: 10.3892/mmr.2016.4776
PMCID: PMC4768997

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