Article
Investigation of the major cytochrome P450 1A2 genetic variant in a healthy Tibetan population in China.
Molecular medicine reports - 1 Jul 2017
Ren Yongchao, Liu Fang, Shi Xugang, Geng Tingting, Yuan Dongya, Wang Li, Kang Longli, Jin Tianbo, Chen Chao
Abstract excerpt
The cytochrome P450 (CYP) 1A2 gene is involved in the metabolism of several carcinogens and clinically important drugs, generating a high potential for pharmacokinetic interactions. Since no data are available for Tibetan aborigines, the present study aimed to investigate the distribution of variant CYP1A2 alleles in a population living in Tibetan region of China. Genotyping analyses of CYP1A2 were conducted in...
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