Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms and phenotypic analysis of cytochrome P450 2D6 in the Tibetan population.

Gene - 15 Sept 2013

Jin Tian-Bo, Ma Li-Feng, Zhang Jia-Yi, Yuan Dong-Ya, Sun Qiang, Zong Ting-Yong, Geng Ting-Ting, Cui Ya-Li, Kang Long-Li, Chen Chao

Abstract excerpt

The cytochrome P450 2D6 enzyme (CYP2D6) metabolizes about 25% of prescribed drugs in the endoplasmic reticulum, and genetic polymorphisms in CYP2D6 can greatly affect its activity and lead to differences among individuals in drug efficacy and adverse drug reactions. To investigate genetic polymorphisms in CYP2D6 among Tibetan Chinese, we directly sequenced the whole gene in 96 unrelated, healthy Tibetans from The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Lod Score

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 23644254
DOI: 10.1016/j.gene.2013.03.110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms and phenotypic analysis of cytochrome P450 2D6 in the Tibetan population.PMID 23644254Read ↗

Genetic polymorphisms of the drug-metabolizing enzyme CYP2J2 in a Tibetan populationSemantic proximity Read ↗

Genetic polymorphisms analysis of CYP2D6 in the Uygur population.Semantic proximity Read ↗

Genetic variations of human CYP2D6 in the Chinese Han population.Semantic proximity Read ↗

Investigation of the major cytochrome P450 1A2 genetic variant in a healthy Tibetan population in China.Semantic proximity Read ↗

Pharmacogenomics of CYP2D6: molecular genetics, interethnic differences and clinical importance.Semantic proximity Read ↗

Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in a Chinese Tibetan population.Semantic proximity Read ↗

Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur.Semantic proximity Read ↗

Genotype‑phenotype analysis of CYP2C19 in the Tibetan population and its potential clinical implications in drug therapy.Semantic proximity Read ↗

Identification and drug metabolic activity evaluation of 12 CYP2D6 allelic variants newly detected in the Chinese population.Semantic proximity Read ↗

Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic populations.Semantic proximity Read ↗

Development and characterization of a rapid and comprehensive genotyping assay to detect the most common variants in cytochrome P450 2D6.Semantic proximity Read ↗

A Review of the Important Role of CYP2D6 in Pharmacogenomics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.