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Genetic polymorphisms of the drug-metabolizing enzyme CYP2J2 in a Tibetan population

1 Oct 2018

Abstract excerpt

As an important metabolic enzyme, it is necessary to investigate the genetic polymorphisms of CYP2J2 among healthy Tibetan individuals. Genetic polymorphisms of CYP2J2 could affect enzyme activity and lead to differences among individual responses to drugs.We sequenced the whole gene of CYP2J2 in 100 unrelated, healthy Tibetan volunteers from the Tibet Autonomous Region and screened for genetic variants in the...

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PMID: 30290621
DOI: 10.1097/md.0000000000012579

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