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Article

Hepatitis B virus preS1 deletion is related to viral replication increase and disease progression.

World journal of gastroenterology - 28 Apr 2015

Lee Seoung-Ae, Kim Ki-Jeong, Kim Hong, Choi Won-Hyuk, Won Yu-Sub, Kim Bum-Joon

Abstract excerpt

AIM: To investigate the clinical implications of hepatitis B virus (HBV) preS1 deletion. METHODS: We developed a fluorescence resonance energy transfer-based real-time polymerase chain reaction (RT-PCR) that can detect four genotypes (wild type, 15-bp, 18-bp and 21-bp deletion). The PCR method was used in two cohorts of Korean chronic HBV subjects with genotype C infections. Cohort I included 292 chronic HBV...

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Identifiers

PMID: 25945020
DOI: 10.3748/wjg.v21.i16.5039
PMCID: PMC4408479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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