Article
Mutations in preS genes of genotype C hepatitis B virus in patients with chronic hepatitis B and hepatocellular carcinoma.
Journal of gastroenterology - 1 Sept 2007
Gao Zhi Yong, Li Tong, Wang Jia, Du Ji Mei, Li Ya Juan, Li Jie, Lu Feng Min, Zhuang Hui
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) preS mutations are frequently isolated from patients with severe forms of liver disease. Meanwhile, genotype C has been shown to cause more serious liver disease than genotype B. This study assesses the frequency of preS mutation in Chinese patients with genotype C chronic HBV infection and its relation to liver damage. METHODS: Seventy-nine persistently infected patients (25...
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