Article
Influence of hepatitis B virus genotypes on the development of preS deletions and advanced liver disease.
Journal of medical virology - 1 Aug 2003
Sugauchi Fuminaka, Ohno Tomoyoshi, Orito Etsuro, Sakugawa Hiroshi, Ichida Takafumi, Komatsu Masafumi, Kuramitsu Tomoyuki, Ueda Ryuzo, Miyakawa Yuzo, Mizokami Masashi
Abstract excerpt
Hepatitis B virus (HBV) mutants with deletions in the preS region have not been evaluated for association with viral genotypes. In a case-control study, HBV DNA samples collected from 80 each of carriers infected with HBV genotype B or C were examined for preS deletions. PreS deletion mutants were found in a total of 37 of 160 (23%) HBV carriers. Carriers with preS deletion mutants were older (56.0 +/- 12.7 vs...
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