Article
Three types of preS1 start codon deletion variants in the natural course of chronic hepatitis B infection.
Journal of gastroenterology and hepatology - 1 Jul 2018
Choe Won Hyeok, Kim Hong, Lee So-Young, Choi Yu-Min, Kwon So Young, Moon Hee Won, Hur Mina, Kim Bum-Joon
Abstract excerpt
BACKGROUND AND AIM: Naturally occurring hepatitis B virus variants carrying a deletion in the preS1 start codon region may evolve during long-lasting virus-host interactions in chronic hepatitis B (CHB). The aim of this study was to determine the immune phase-specific prevalent patterns of preS1 start codon deletion variants and related factors during the natural course of CHB. METHODS: A total of 399 CHB...
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