Article
PreS1 deleted variants of hepatitis B virus in patients with chronic hepatitis.
Journal of hepatology - 1 Mar 1994
Nakajima E, Minami M, Ochiya T, Kagawa K, Okanoue T
Abstract excerpt
Defective hepatitis B virus lacking 183 bases of the 3'-terminus part of the preS1 region was found in the sera of two patients with chronic hepatitis B virus infection. Results of sequencing analysis of samples with or without polymerase chain reaction yielded the same result, proving that this deletion was not due to an artifact obtained during polymerase chain reaction. One of the deletion ends lay in TCAGG...
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