Article
PreS1 deleted variants of hepatitis B virus in patients with chronic hepatitis.
Journal of hepatology - 1 Mar 1994
Nakajima E, Minami M, Ochiya T, Kagawa K, Okanoue T
Abstract excerpt
Defective hepatitis B virus lacking 183 bases of the 3'-terminus part of the preS1 region was found in the sera of two patients with chronic hepatitis B virus infection. Results of sequencing analysis of samples with or without polymerase chain reaction yielded the same result, proving that this...
Topics
- Base Sequence
- Chronic Disease
- DNA, Viral
- Gene Deletion
- Genome, Viral
- Hepatitis B
- Hepatitis B Surface Antigens
- Hepatitis B virus
- Humans
- Interferons
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Protein Precursors
- Viral Envelope Proteins