Article
Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients.
PloS one - 1 Jan 2022
Thi Cam Huong Nguyen, Trung Nguyen Quang, Luong Bac An, Tram Duong Bich, Vu Hoang Anh, Bui Hoang Huu, Pham Thi Le Hoa
Abstract excerpt
BACKGROUND: Chronic hepatitis B virus (CHB) infection is a major health problem and leading cause of hepatocellular carcinoma (HCC) worldwide. Several point and deletion mutations on the PreS/S gene have been intensively considered associated with HCC. This study aimed to describe the characteristics of HBV PreS/S mutations in Vietnamese CHB-infected patients and their association with HCC. METHODS: This...
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