Article
The preS deletion of hepatitis B virus (HBV) is associated with liver fibrosis progression in patients with chronic HBV infection.
Hepatology international - 1 Mar 2018
Li Fan, Li Xiaodong, Yan Tao, Liu Yan, Cheng Yongqian, Xu Zhihui, Shao Qing, Liao Hao, Huang Pengyu, Li Jin, Chen Guo-Feng, Xu Dongping
Abstract excerpt
BACKGROUND AND AIMS: Limited data are available regarding the association of hepatitis B virus (HBV) mutations with liver fibrosis in HBV infection. The study aimed to clarify whether HBV preS deletion mutation is associated with liver fibrosis progression. METHODS: A total of 469 patients were enrolled, including 324 with chronic hepatitis B (CHB), 28 with HBV-related compensated liver cirrhosis (LC), and 117...
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