Folate pathway gene polymorphisms and risk of childhood brain tumors: results from an Australian case-control study.

doi:10.1158/1055-9965.EPI-14-1248

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Folate pathway gene polymorphisms and risk of childhood brain tumors: results from an Australian case-control study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2015

Greenop Kathryn R, Scott Rodney J, Attia John, Bower Carol, de Klerk Nicholas H, Norris Murray D, Haber Michelle, Jamieson Sarra E, van Bockxmeer Frank M, Gottardo Nicholas G, Ashton Lesley J, Armstrong Bruce K, Milne Elizabeth

Abstract excerpt

BACKGROUND: Recent research suggests that maternal folic acid supplementation is associated with a reduced risk of childhood brain tumors (CBT); polymorphisms in folate pathway genes could modify this association or directly influence CBT risk. METHODS: Associations between risk of CBT and folate pathway polymorphisms were investigated in a population-based case-control study in Australia (2005-2010). Cases were...

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PMID: 25809864
DOI: 10.1158/1055-9965.EPI-14-1248

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MTRR
MTHFR
MTR
CBS
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