Article
Folate pathway genetic polymorphisms are related to attention disorders in childhood leukemia survivors.
The Journal of pediatrics - 1 Jan 2008
Krull Kevin R, Brouwers Pim, Jain Neelam, Zhang Linna, Bomgaars Lisa, Dreyer ZoAnn, Mahoney Donald, Bottomley Sarah, Okcu M Fatih
Abstract excerpt
OBJECTIVE: To test the hypothesis that 5,10-methylenetetrahydroreductase (MTHFR) polymorphisms can partially explain the individual variation in developing attention-deficit/hyperactivity disorder (ADHD) after acute lymphoblastic leukemia (ALL) therapy. STUDY DESIGN: Parents of 48 survivors of childhood ALL completed a clinical diagnostic process to identify subtypes of ADHD. Genotyping was performed with...
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