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Article

Association between MTHFR 677C>T polymorphism and risk of gliomas: evidence from a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013

Lu Qiong, Dai Dongwei, Zhao Wenyuan, Wang Laixing, Yue Zhijian, Chen Xin, Han Guosheng, Hao Bin, Yang Pengfei, Deng Anmei, Liu Jianmin

Abstract excerpt

Folate metabolism plays an important role in carcinogenesis. Methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism is a genetic alteration in an enzyme involved in folate metabolism, but its effect on risk of gliomas is still uncertain. To shed some light on these contradictory results from previous studies, we performed a meta-analysis of published data investigating the association between MTHFR...

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Source

Identifiers

PMID: 23765760
DOI: 10.1007/s13277-013-0838-4

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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