Article

Tracking mobilization uncovers an evolutionarily conserved mechanism in suppressing transpositions during somatic development

2025-02-07

Abstract excerpt

Transposon mobilizations could cause gene mutations and even genomic instability, whose aberrant activation is tightly linked with cancer, neurodegenerative disorder and other pathologies. However, the precise suppression mechanisms of transposon mobilizations during somatic development throughout evolution remain largely obscure. Here, by spatiotemporally monitoring transpositions with single-cell resolution, we...

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Literature Corpus work: f13f7e34-cc5c-53b9-a19c-d1fa84d4948b
DOI: 10.1101/2025.02.07.636160

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