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Article

Noncoding RNA-nucleated heterochromatin spreading is intrinsically labile and requires accessory elements for epigenetic stability.

eLife - 18 Jul 2018

Greenstein R A, Jones Stephen K, Spivey Eric C, Rybarski James R, Finkelstein Ilya J, Al-Sady Bassem

Abstract excerpt

The heterochromatin spreading reaction is a central contributor to the formation of gene-repressive structures, which are re-established with high positional precision, or fidelity, following replication. How the spreading reaction contributes to this fidelity is not clear. To resolve the origins of stable inheritance of repression, we probed the intrinsic character of spreading events in fission yeast using a...

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Identifiers

PMID: 30020075
DOI: 10.7554/eLife.32948
PMCID: PMC6070336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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