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Article

The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast.

The Journal of biological chemistry - 13 Oct 2017

Seo Hogyu David, Choi Yoonjung, Kim Minhoo, Kang Keunsoo, Urano Takeshi, Lee Daeyoup

Abstract excerpt

Cumulative evidence suggests that non-proteolytic functions of the proteasome are involved in transcriptional regulation, mRNA export, and ubiquitin-dependent histone modification and thereby modulate the intracellular levels of regulatory proteins implicated in controlling key cellular functions. To date, the non-proteolytic roles of the proteasome have been mainly investigated in euchromatin; their effects on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28784663
DOI: 10.1074/jbc.M117.790824
PMCID: PMC5641893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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