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Article

Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells.

Scientific reports - 16 Mar 2015

Fujii Setsuko, Nishikawa-Torikai Satomi, Futatsugi Yoko, Toyooka Yayoi, Yamane Mariko, Ohtsuka Satoshi, Niwa Hitoshi

Abstract excerpt

Nuclear receptor subfamily 0, group B, member 1 (Nr0b1, also known as Dax1) is regarded as an important component of the transcription factor network that governs pluripotency in mouse embryonic stem (ES) cells. Here we generated inducible knockout ES cells for Nr0b1 using the Cre-loxP system and analyzed its precise function. We succeeded in establishing the Nr0b1-null ES cells and confirmed their pluripotency...

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Identifiers

PMID: 25772165
DOI: 10.1038/srep09146
PMCID: PMC5390923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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