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Article

Critical roles of coactivator p300 in mouse embryonic stem cell differentiation and Nanog expression.

The Journal of biological chemistry - 3 Apr 2009

Zhong Xiaomin, Jin Ying

Abstract excerpt

p300 is a well known histone acetyltransferase and coactivator that plays pivotal roles in many physiological processes. Despite extensive research for the functions of p300 in embryogenesis and transcription regulation, its roles in regulating embryonic stem (ES) cell pluripotency are poorly understood. To address this issue, we investigated the self-renewal ability and early differentiation process in both...

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Share to Acetylation
Share to E1A-Associated p300 Protein
Share to Embryonic Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene Expression Regulation, Developmental

Share to Histones

Share to Homeodomain Proteins

Share to Nanog Homeobox Protein

Source

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Identifiers

PMID: 19150979
DOI: 10.1074/jbc.M805562200
PMCID: PMC2666568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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