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Article

Long non-coding RNAs potentially function synergistically in the cellular reprogramming of SCNT embryos

23 Aug 2018

Abstract excerpt

BACKGROUND: Long non-coding RNAs (lncRNAs), a type of epigenetic regulator, are thought to play important roles in embryonic development in mice, and several developmental defects are associated with epigenetic modification disorders. The most dramatic epigenetic reprogramming event occurs during somatic cell nuclear transfer (SCNT) when the expression profile of a differentiated cell is abolished, and a newly...

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PMID: 30139326
DOI: 10.1186/s12864-018-5021-2

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