Article
Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells.
BMC developmental biology - 24 Apr 2008
Masui Shinji, Ohtsuka Satoshi, Yagi Rika, Takahashi Kadue, Ko Minoru S H, Niwa Hitoshi
Abstract excerpt
BACKGROUND: Rex1/Zfp42 has been extensively used as a marker for the undifferentiated state of pluripotent stem cells. However, its function in pluripotent stem cells including embryonic stem (ES) cells remained unclear although its involvement in visceral endoderm differentiation in F9 embryonal carcinoma (EC) cells was reported. RESULTS: We showed the function of Rex1 in mouse ES cells as well as in embryos...
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