Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Novel Role for Kruppel-like Factor 14 (KLF14) in T-Regulatory Cell Differentiation

29 Dec 2014

Abstract excerpt

Background & Aims Kruppel-like Factor 14 (KLF14) proteins function as epigenetic reprogramming factors during cell differentiation in many cell populations and in engineered induced pluripotent stem cells. In this study, we determined the function of KLF14 in the regulation of forkhead box protein 3 (FOXP3), a transcription factor critical for T regulatory (Treg) cell differentiation. Methods We studied the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Syndromes and Imprinting
Share to Kruppel-like factors research
Share to Lipid metabolism and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25750932
DOI: 10.1016/j.jcmgh.2014.12.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Novel Role for Kruppel-like Factor 14 (KLF14) in T-Regulatory Cell DifferentiationPMID 25750932Read ↗

Histone methylation mediates plasticity of human FOXP3(+) regulatory T cells by modulating signature gene expressions.Semantic proximity Read ↗

Cis-Regulatory Element and Transcription Factor Circuitry Required for Cell-Type Specific Expression of FOXP3Semantic proximity Read ↗

Optimized CRISPR-mediated gene knock-in reveals FOXP3-independent control of human Treg identitySemantic proximity Read ↗

Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases.Semantic proximity Read ↗

Molecular control of regulatory T cell development and function.Semantic proximity Read ↗

Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity.Semantic proximity Read ↗

Forkhead box P3: the peacekeeper of the immune system.Semantic proximity Read ↗

Epigenetic mechanisms of regulation of Foxp3 expression.Semantic proximity Read ↗

Transcriptional control of regulatory T-cell differentiation.Semantic proximity Read ↗

Krüppel‐like factor 4 (KLF4) directly regulates proliferation in thymocyte development and IL‐17 expression during Th17 differentiationSemantic proximity Read ↗

Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene.Semantic proximity Read ↗

Post-Translational Regulations of Foxp3 in Treg Cells and Their Therapeutic Applications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.