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Article

Post-Translational Regulations of Foxp3 in Treg Cells and Their Therapeutic Applications.

Frontiers in immunology - 1 Jan 2021

Dong Yi, Yang Cuiping, Pan Fan

Abstract excerpt

Regulatory T (Treg) cells are indispensable for immune homeostasis due to their roles in peripheral tolerance. As the master transcription factor of Treg cells, Forkhead box P3 (Foxp3) strongly regulates Treg function and plasticity. Because of this, considerable research efforts have been directed at elucidating the mechanisms controlling Foxp3 and its co-regulators. Such work is not only advancing our...

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Share to Phenotype
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Processing, Post-Translational

Share to T-Lymphocytes, Regulatory

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Identifiers

PMID: 33912156
DOI: 10.3389/fimmu.2021.626172
PMCID: PMC8071870

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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