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Article

Epigenetic mechanisms of regulation of Foxp3 expression.

Blood - 29 Oct 2009

Lal Girdhari, Bromberg Jonathan S

Abstract excerpt

Regulatory T cells play important roles in the control of autoimmunity and maintenance of transplantation tolerance. Foxp3, a member of the forkhead/winged-helix family of transcription factors, acts as the master regulator for regulatory T-cell (Treg) development and function. Mutation of the Foxp3 gene causes the scurfy phenotype in mouse and IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy,...

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Source

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Identifiers

PMID: 19641188
DOI: 10.1182/blood-2009-05-219584
PMCID: PMC2773485

Genes

DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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