Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular control of regulatory T cell development and function.

Current opinion in immunology - 1 Dec 2017

Kitagawa Yohko, Sakaguchi Shimon

Abstract excerpt

Treg cells expressing the transcription factor Foxp3 are essential for immunological tolerance and homeostasis. Recent genome-wide studies have revealed that Foxp3+ natural Treg cells possess a number of unique transcriptional and epigenetic features, which appear to be acquired along the course of Treg cell development and maintained throughout their lifespan. These studies also provide novel insights into how...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases
Share to Cell Self Renewal
Share to Forkhead Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Homeostasis

Share to Immune Tolerance

Share to Lymphocyte Activation

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 29065384
DOI: 10.1016/j.coi.2017.10.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular control of regulatory T cell development and function.PMID 29065384Read ↗

Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases.Semantic proximity Read ↗

Regulatory T cells and Foxp3.Semantic proximity Read ↗

Transcriptional control of regulatory T-cell differentiation.Semantic proximity Read ↗

Forkhead box P3: the peacekeeper of the immune system.Semantic proximity Read ↗

Foxp3: a genetic foundation for regulatory T cell differentiation and function.Semantic proximity Read ↗

Control of regulatory T cell development by the transcription factor Foxp3.Semantic proximity Read ↗

Epigenetic mechanisms of regulation of Foxp3 expression.Semantic proximity Read ↗

Histone methylation mediates plasticity of human FOXP3(+) regulatory T cells by modulating signature gene expressions.Semantic proximity Read ↗

Preserved suppressive function despite loss of Foxp3: insights into the identity of regulatory T cellsSemantic proximity Read ↗

FOXP3: genetic and epigenetic implications for autoimmunity.Semantic proximity Read ↗

Foxp3 in the Immune SystemSemantic proximity Read ↗

Revisiting regulatory T cells in type 1 diabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.