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Article

Viremic control and viral coreceptor usage in two HIV-1-infected persons homozygous for CCR5 Δ32.

AIDS (London, England) - 15 May 2015

Henrich Timothy J, Hanhauser Emily, Hu Zixin, Stellbrink Hans-Jürgen, Noah Christian, Martin Jeffrey N, Deeks Steven G, Kuritzkes Daniel R, Pereyra Florencia

Abstract excerpt

OBJECTIVES: To determine viral and immune factors involved in transmission and control of HIV-1 infection in persons without functional CCR5. DESIGN: Understanding transmission and control of HIV-1 in persons homozygous for CCR5(Δ32) is important given efforts to develop HIV-1 curative therapies aimed at modifying or disrupting CCR5 expression. METHODS: We identified two HIV-infected CCR5(Δ32/Δ32) individuals...

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Topics

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Share to CD4 Lymphocyte Count
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Receptors, CCR5

Share to Receptors, CXCR4

Share to Viral Load

Share to Viremia

Source

Open in PubMed Open full text

Identifiers

PMID: 25730507
DOI: 10.1097/QAD.0000000000000629
PMCID: PMC4473772

Genes

CCR5
CXCR4
CXCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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