Article
HIV and the CCR5-Delta32 resistance allele.
FEMS microbiology letters - 1 Dec 2004
de Silva Eric, Stumpf Michael P H
Abstract excerpt
The combination of molecular biology, epidemiology, virology, evolutionary and population genetics has enabled us to understand the delicate interplay between HIV and the CCR5-Delta32 HIV resistance allele. We here review and collect from the different approaches to show how they can be combined to elucidate the interaction between host and pathogen genetics in this system. We will present an overview of the...
Topics
- Alleles
- Amino Acid Sequence
- Antiretroviral Therapy, Highly Active
- Genetics, Population
- HIV Infections
- Humans
- Molecular Sequence Data
- Receptors, CCR5
- Selection, Genetic