The rs7517847 polymorphism in the IL-23R gene is associated with gout in a Chinese Han male population.

doi:10.3109/14397595.2014.964823

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Article

The rs7517847 polymorphism in the IL-23R gene is associated with gout in a Chinese Han male population.

Modern rheumatology - 1 May 2015

Liu Shiguo, He Hongmei, Yu Renchao, Han Lin, Wang Can, Cui Ying, Li Changgui

Abstract excerpt

OBJECTIVES: Gout is a polygenic auto-inflammatory disease, in which inflammation plays an important role in disease pathogenesis. The cytokine interleukin (IL)-23 promotes inflammation and helps to guide inflammatory cells, while studies have shown that the IL-23R gene is associated with susceptibility to several immune-related diseases. This study aimed to determine whether the IL-23R rs7517847 (G/T)...

Topics

Adult
Aged
Alleles
Asian People
China
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Gout
Humans
Male
Middle Aged
Phenotype
Polymorphism, Single Nucleotide
Receptors, Interleukin

Source

Open in PubMed

Identifiers

PMID: 25661540
DOI: 10.3109/14397595.2014.964823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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