Article
The rs7517847 polymorphism in the IL-23R gene is associated with gout in a Chinese Han male population.
Modern rheumatology - 1 May 2015
Liu Shiguo, He Hongmei, Yu Renchao, Han Lin, Wang Can, Cui Ying, Li Changgui
Abstract excerpt
OBJECTIVES: Gout is a polygenic auto-inflammatory disease, in which inflammation plays an important role in disease pathogenesis. The cytokine interleukin (IL)-23 promotes inflammation and helps to guide inflammatory cells, while studies have shown that the IL-23R gene is associated with susceptibility to several immune-related diseases. This study aimed to determine whether the IL-23R rs7517847 (G/T)...
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