Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations between interleukin and interleukin receptor gene polymorphisms and risk of gout.

Scientific reports - 24 Sept 2015

Liu Shiguo, Zhou Zheng, Wang Can, Guo Mingzhen, Chu Nan, Li Changgui

Abstract excerpt

Gout is a self-limiting, auto-inflammatory arthritis induced by the deposition of monosodium urate crystals in the synovial fluid and periarticular tissues. The aim of this study was to investigate the associations between genetic variants in the interleukin (IL) and interleukin receptor (ILR) genes IL-33, IL-1RL1, IL-23R, and signal transducer and activator of transcription 4 (STAT4) and susceptibility to gout...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Case-Control Studies
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Interleukins

Share to Receptors, Interleukin

Source

Open in PubMed Open full text

Identifiers

PMID: 26399911
DOI: 10.1038/srep13887
PMCID: PMC4585862

Genes

STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations between interleukin and interleukin receptor gene polymorphisms and risk of gout.PMID 26399911Read ↗

The rs7517847 polymorphism in the IL-23R gene is associated with gout in a Chinese Han male population.Semantic proximity Read ↗

Associations Between the NLRP3 and IL-1β Gene Polymorphisms and Gout SusceptibilitySemantic proximity Read ↗

Association between IL-33 Gene Polymorphisms (rs1929992, rs7044343) and Systemic Lupus Erythematosus in a Chinese Han Population.Semantic proximity Read ↗

Interleukin (IL)-23 receptor is a major susceptibility gene for Graves' ophthalmopathy: the IL-23/T-helper 17 axis extends to thyroid autoimmunity.Semantic proximity Read ↗

Polymorphisms in the vitamin D receptor and risk of gout in Chinese Han male population.Semantic proximity Read ↗

Genetic Analysis of IL-17 Gene Polymorphisms in Gout in a Male Chinese Han Population.Semantic proximity Read ↗

Interleukin 23 receptor gene polymorphisms and their role in the inflammatory status of rheumatoid arthritis patients in an Iranian population.Semantic proximity Read ↗

IL-33 Gene Polymorphisms as Potential Biomarkers of Disease Susceptibility and Response to TNF Inhibitors in Rheumatoid Arthritis, Ankylosing Spondylitis, and Psoriatic Arthritis Patients.Semantic proximity Read ↗

IL-8 -251T/A and IL-12B 1188A/C polymorphisms are associated with gout in a Chinese male population.Semantic proximity Read ↗

Single nucleotide polymorphisms of the interleukin-33 (IL-33) gene are associated with ankylosing spondylitis in Chinese individuals: a case-control pilot study.Semantic proximity Read ↗

Association of TLR4 Gene rs2149356 polymorphism with primary gouty arthritis in a case-control study.Semantic proximity Read ↗

A candidate gene approach identifies an IL33 genetic variant as a novel genetic risk factor for GCA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.